Try DGX Spark playbooks using Nix on DGX OS, or install NixOS on your DGX Spark for the full Nix experience. The repository provides USB images and a NixOS module with settings for DGX Spark systems.

This works on the NVIDIA DGX Spark itself and also on the Asus Ascent GX10.

See my 5 minute lightning talk from Planet Nix for an intro: https://youtu.be/AvK_gi_snJE?si=MPKv3iiuS9B5elIE